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The best way of using Cardarine for ultimate results is to take advantage of the way it works as an excellent support compound in a cycle that also includes either SARMs or anabolic steroids."With its superior molecular structure, Cardarine is a very good compound for adding to a cycle," says Nandini.A well established study of a compound called C16-DGLT (decreasing DGLT and increasing testosterone and estradiol through deactivation of the aromatase enzyme) is published in the journal Steroid Biochem Mol Biol.The paper is the first to look at these compounds together in a cycle. The authors found that the compound did not induce adverse side effects or toxicity in rats, even when used alone."A cycle of C16-DGLT and androgen receptor activators or androgen analogues was used to determine if a combination of C16-DGLT and androgen receptor activators might decrease or reverse the effects of anabolic steroids on muscle mass and strength in male mice," the authors report.Interestingly, they found that when tested together, C16-DGLT led to increased performance and lean mass gain and increased the expression of testosterone in both serum and muscle, in addition to improving the response to endurance and strength exercises."Cardarine improves a number of parameters after a cycle without producing adverse effects. Therefore, it is considered safe and potentially useful for use in improving lean muscle mass by both human and laboratory models of muscle growth," says Nandini.The researchers stress that their findings do not imply that Cardarine is better tolerated than other steroidal compounds to which it may be compared and as such should not be used in the same dose as others, as long as it is taken in the correct dosages for its intended purpose."The safety of Cardarine in humans must be assessed in order to ensure it does not adversely affect health, safety and quality of life in healthy young males and females. These findings of improved exercise performance and reduction of fat mass with Cardarine will be of interest to our partners, health practitioners and researchers in the field of human and animal research, as well as future and past clinical trials," says Nandini.###Nandini has recently been featured as a senior fellow and researcher in the Journal of the American Society of Endocrinology. She is a professor in the Department of Biochemistry and Molecular Genetics at the University of California, Irvine, who specializes in the studies of hormones in animals and cancer. She is also director of the Clinical Gene Therapy Program within the University of Colorado Division of Hematology and Cancer ResearchRelated Article: